Name_________________________
SPRING SEMESTER ‘12
BIO 366 EXAM I - FEBRUARY 14, 2012
MULTIPLE CHOICE QUESTIONS (4 points each, only one correct choice)
1. Which of the following RNA characteristics is responsible for breakage of
phosphodiester bonds under alkaline conditions?
a. presence of uridine in RNA
b. RNA is single-stranded
c. RNA has few hydrogen bonds
d. both the 2’ and 3’ positions of the ribose have a hydroxyl group
e. the 2’ position of ribose lacks a hydroxyl group
2. Which of the following statements regarding DNA structure is incorrect?
a. pyrimidine bases have a less complex ring structure than purines
b. A•T base pairs have two hydrogen bonds
c. B DNA duplex structure is a left-handed helix
d. one turn of the B DNA duplex structure corresponds to ~10.5 base pairs
e. B DNA duplex structure displays a major groove and a minor groove
3. Which of the following is a feature of DNA synthesis but not RNA synthesis?
a. precursor nucleoside triphosphates are cleaved between the alpha and beta phosphates
b. newly synthesized chains grow in the 5’ to 3’ direction
c. duplex DNA requires melting at the site of synthesis
d. thymidine is incorporated when the template base is adenine
e. guanine is incorporated when the template base is cytidine
4. Which of the following is found in eukaryotic mRNAs but not prokaryotic mRNAs?
a. 7-methylguanylate cap
b. 5’ untranslated region
c. 5’ triphosphate
d. AUG start site for translation
e. multiple genes translated independently
5. Which of the following correctly describes the core subunit composition of E. coli
RNA polymerase?
a. four identical subunits
b. four non-identical subunits
c. three identical subunits
d. three non-identical subunits
e. more than four subunits
1
