Standard Amino Acid
Neutral non-polar
Neutral polar
Acidic
Basic
Glycine ,Alanine,Valine,
Leucine, Isoleucine,
Phenylalanine,
Tryptophan, Methionine,
Cysteine,Proline
R groups do not bear +/- charge
R group interact poorly with water
Maintaining three-dimensional structure of protein
Serine,
Threonine
,
Tyrosine,
Contain polar OH group
Participate in hydrogen bonding
-OH groups of Serine & threonine -
points for attaching carbohydrates
Asparagine
,Glutamine
Amide derivative
Amide functional group highly polar
Aspartate,
Glutamate
Carboxylate group as a side chain
Negatively charged at physiological pH
Lysine, Arginine, Histidine
Positively charge at physiological pH
Histidine - weak base
Partially ionised at pH 7
Guanidino group of Arginine
Permanently protonated at physiological pH
Does not function in acid base reaction
