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Use this as your micro study guide for quiz 3
Typology: Study notes
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Genome
cells
undergoDNA
replication
transcription translation to
multiply
Divide
deoxy
ribonucleic
deoxyribose phosphate
nucleobase
5Pa
hate
Yarbon
VRNA
ribonucleic acid riboseuracil
RNAmessenger
RNA
ribosomal RNA
TRNA
transferRNA
forks
theres 2 at
each
shaped
meetat terminating
whencomplet
replication
starts
the
of
replication
strand
helicase
helix
primaseenzymethat
synthesizesRNA sequences
called
primers
At
helicase
unwindsDNA
Proteins
bindtothe
DNA
strands
to
keep
them
aph
case so
primate polymerase
Ligase
3
primase
makes
strands
4
polymerase
builds
new
strands 5 to
Ligase
gaps
between okazakifragments sealing
together
DNAtranscription
occurs in
nucleus
can
go
out
nucleus
into
cytoplasm
where it
attaches
to a
ribosome
ribosomes make protein
2
ribosomesmade
protein
for
translation
mrna
n'Biome
translation
MRNAinprokaryotes
gene
or
Translation
1 tRNA carryamino
acids on them
actupon
signal provided
by
mRNA
forth
a
Idle
Phi
reads
bases
codon
time andwill
provide the
complimentary base
pair
Sigma
factor recognizes
promoter
Quorum sensing
cell
signaling
membrane
spanning
sensorchanges
internal
region
phosphorylates Amino
Acids
response regulator
turns genesonoff
phosphate
group
transferred
sensor
antigenic
variation
strategy
pathogens
evade
changing their
surface
antigens
theyre
unrecogniza
variation
switches genes
on off
operon setof
regulated genes
transcribed
as
regulon separate
operons
controlled
a single
regulatory
mechanism
Constituitive
enzymes
constantlysynthesized
Inducibleenzymes
not
routinley
produced
made
needed
repressible enzymes constantly
produced
off when
not
needed
2
most
common
waysto
control transcription
alternative
sigma
factor
standard
Sigma
factor
DNA
Binding
protein
canactas
repressors
activators
Induction
blockstranscription
repression
cant
blocktranscription without
repressor
sensing
glucose
levels
throughtransporter
operon hasan
activatorcalled catabolite activator
protein
2 CAPbinds
activator
binding
is
required
transcription
CAP
functions
when
bound
by
cAMPcAMP madewhen
glucose
auxotroph
deletion of gene
environmentdoesntcause
mutation
base
substitution
incorrectnucleotideincorporated
during DNA
synthesis
leads
silent
missensenonsense
mutations
frameshift mutation premature
stop
codon
transposons
jumping
genes
transposition
intercatalating agents
cause frameshift
mutations
Base
excision repair
glycosylase
removesdamaged
nucleobase
2 main
approaches
to
isolate
indirect
selection
ames test
measures effect
of
chemical
reversion
rate
Genes
are
transferred through
transformationBY
a
transduction
Yaffa
conjugationcells
transformation
uptakeof
naked DNA
transduction
of
bacterial
genes
by
bacteriophages
Conjugation DNA transfer
R
resistance
systems
clusters of
regularly
interspersed
short
palindromic
repeats
Vivon
complete
viralparticle
outside host
nucleicacidprotein
coat
enveloped
viruslipidbilayerenvelope
host
non
enveloped
virus
lacks
envelope more
resistant
to
disinfectants
lytic
phage
infectionswhen
it
host cell
lyses
temperate
phage
infection infected
lysogeny
consequences immune to
superinfection
infected
by
phage
know
Hep
Hep
C