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NMTT 2167 Practicum III – Final Examination (Take-away Notes)
Similar to adenosine, the use of dipyridamole in patients with severe or uncontrolled hypertension may result in undesirable hypotensive episodes. In contrast, the preferred pharmacologic stress agent for patients with hypertension is typically regadenoson (Lexiscan): Regadenoson is a selective A2A adenosine receptor agonist that has a more favorable hemodynamic profile, with less pronounced effects on blood pressure and heart rate compared to other stress agents. Studies have shown that regadenoson can be used safely in patients with hypertension, with a lower incidence of significant hypotension or other adverse cardiovascular events.