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Test 1 Patho Maryville Nurs 611 2024-2025 Questions & Correct Answers Already Graded A+.docx
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Antidiuretic Hormone (ADH) - ANSSecretion of ADH and the perception of thirst are stimulated by an increase in plasma osmolality Apoptosis - ANSprogrammed death such as inflammation ATP - ANSAdenosine Triphosphate is energy that needs oxygen. aerobic metabolism Atrophy - ANSphysiologic atrophy of the thymus gland in childhood Dysplasia - ANSNot a form of cellular adaptation Effect of muscular atrophy on Na+ and K+ levels - ANSF&E: Total body K+ concentration decreases r/t decreased cellular mass An increased Na+/K+ ratio suggests that the decreased cellular mass is accompanied by an increased extracellular compartment Ethanol - ANSLiver enzymes metabolize ethanol to acetaldehyde which causes hepatic cellular dysfunction. Peroxisomes help to detoxify ethanol. Without peroxisomes the ethanol is turned into fat in the liver (fatty liver) explain the process that occurs in response to hypernatremia - ANSWater is drawn from the intracellular space to the extravascular space in an effort to restore fluid balance. Water follows Na+ outside of the cell causing it to shrink Free radical - ANSAn electrically uncharged atom(s) that has an unpaired electron. Having one electron that is unpaired makes the atom unstable so the atom either has to take an electron from another molecule or give one away Hypernatremia; what causes it - ANSNa+ greater than 147 mEq/L inadequate free water intake; inappropriate administration of hypertonic saline solution; over secretion of aldosterone Hyperplasia - ANSincrease in number of cells Compensatory hyperplasia would be the regeneration of liver cells when 70% of liver is removed Pathologic hyperplasia would be seen in the endometrium Hypertrophy - ANSincrease in cell size Physiologic hypertrophy would be increase in myocardial cell size r/t endurance training
Pathologic hypertrophy would be secondary to disease such as HTN Hyponatremia; what causes it - ANSNa+ less than 135 mEq/L diuretics, vomiting, diarrhea (losing fluids) hypotonic IV solutions, kidney failure, heart failure, liver failure Metaplasia - ANSReplacement of different cells (think metamorphosis) Ex: normal columnar ciliated epithelial cells of the bronchial lining have been replaced by stratified squamous epithelial cells Muscular Atrophy - ANSaka Sarcopenia Stiffness or rigidity of systems Peripheral vascular resistance increases Decreased production of HCL and delayed emptying of stomach Decreased immune response Necrosis - ANScellular injury such as MI, hypoxia Oncotic pressure - ANSinfluenced by plasma proteins; a reduction in plasma oncotic pressure causes low plasma albumin/protein and leads to edema RAAS; Explain this system - ANSRenin Angiotensin Aldosterone System When there is a drop in blood pressure the JG cells release renin in response to stimulation from sympathetic nerve cells. The decreased perfusion or pressure as well as low Na+ activates the macula densa cells to release prostaglandin signs and symptoms of hyponatremia - ANSheadache, lethargy, confusion; seizures, coma, cerebral edema What are natriuretic peptides - ANShormones that decrease blood pressure and increase Na+ and water excretion (antagonist of the RAAS because RAAS works to increase BP and NP decrease) atrial natriuretic peptide (ANP) produced by the myocardial atria brain natriuretic peptide (BNP) produced by the myocardial ventricles urodilatin within the kidney What are the clinical manifestations of hypernatremia - ANSconfusion, convulsions, coma, cerebral hemorrhage What are the s/sx of dehydration (decreased perfusion) - ANSheadache, thirst, dry skin and mucous membranes, weight loss, decreased or concentrated urine, tachycardia, weak pulses, postural hypotension What happens when oxygen reserves are depleted? - ANSanaerobic metabolism (glycolysis)