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Understanding primary skin lesions, Exams of Dermatology

Macules may precede papules in cases of pyoderma. In atopic dogs erythematous macules may be found in the groins or in the palmer and plantar interdigitae.

Typology: Exams

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Most often we clinicians are not presented
with a dog in the early stages of skin
disease. Rather, the disease has been
present for some time. Thus, the effects of self
trauma, and the ongoing nature of the disease,
results in secondary lesions such as crust and scale,
alopecia and self trauma. Consider the Cocker
Spaniel in Figure 1a. This dog had a 6 month
history of a moderately pruritic progressive dermat-
itis. At presentation the most obvious signs were
almost total alopecia and crusting-both secondary
lesions and of little diagnostic help. Careful search,
however, revealed a few pustules, as Figure 1b.
These pustules were the primary lesions of the
dermatitis, in this case a drug eruption.
In some cases the pattern of the secondary
lesions may suggest a diagnosis, while not being
in themselves of definitive diagnosis value. Thus
the bilateral excoriations on the Rottweiler in
Figure 2 were a consequence of flea bite hyper-
sensitivity.
Primary lesions
Macules
Areas of discoloration of the skin, less than 1 cm in
diameter. Typically erythematous, but they may
be hyperpigmented. Figure 3 shows conjoining
erythematous macules in a dog with hyperadreno-
corticism. Macules may precede papules in cases
of pyoderma. In atopic dogs erythematous
macules may be found in the groins or in the
palmer and plantar interdigitae.
Papule
Papules are defined as small, discrete, palpably solid
elevations on the skin surface (Figure 4a). Some
papules may be neoplastic (Figure 4b). Most
commonly, and particularly in the groins, they
precede pustules. Crusted papules may follow
vesicles or pustules. In the dog crusted papules
outnumber pustules in superficial pyoderma.
Superficial pyoderma is uncommon in the cat
and in this species the most common underlying
cause of a crusted papular dermatitis is flea bite
hypersensitivity (Figure 5).
Nodule
A well-defined, solid elevation (Figure 6), greater
than 1 cm in diameter. Nodules are typically,
although not exclusively, associated with neoplasia.
Pustule
Pustules (Figure 7) are the primary lesions of
superficial pyoderma, although often outnumbered
by papules, crusted papules (Figure 8) and epi-
dermal collarettes (Figure 9). Pustules are the
primary lesions of pemphigus foliaceus but are
rarely accompanied by epidermal collarettes in this
disease. Pustules are also found in association
with other conditions associated with secondary
infection such as demodicosis.
Vol 18 No 1 / / 2008 / / Veterinary Focus / / 47
CUT-OUT AND KEEP GUIDE
Understanding
primary skin lesions
By Richard Harvey
Figure 2. More or
less symmetrical
crusting and linear
alopecia in a
Rottweiler with flea
bite hypersensitivity.
Figures 1 a and 1 b. Almost total alopecia and crusting on a Cocker Spaniel with a 6
month history. Careful examination of the dog revealed a few pustules (Figure 1b).
ab
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ost often we clinicians are not presented with a dog in the early stages of skin disease. Rather, the disease has been present for some time. Thus, the effects of self trauma, and the ongoing nature of the disease, results in secondary lesions such as crust and scale, alopecia and self trauma. Consider the Cocker Spaniel in Figure 1a. This dog had a 6 month history of a moderately pruritic progressive dermat- itis. At presentation the most obvious signs were almost total alopecia and crusting-both secondary lesions and of little diagnostic help. Careful search, however, revealed a few pustules, as Figure 1b. These pustules were the primary lesions of the dermatitis, in this case a drug eruption.

In some cases the pattern of the secondary lesions may suggest a diagnosis, while not being in themselves of definitive diagnosis value. Thus the bilateral excoriations on the Rottweiler in Figure 2 were a consequence of flea bite hyper- sensitivity.

Primary lesions

Macules Areas of discoloration of the skin, less than 1 cm in diameter. Typically erythematous, but they may be hyperpigmented. Figure 3 shows conjoining erythematous macules in a dog with hyperadreno- corticism. Macules may precede papules in cases of pyoderma. In atopic dogs erythematous

macules may be found in the groins or in the palmer and plantar interdigitae.

Papule Papules are defined as small, discrete, palpably solid elevations on the skin surface (Figure 4a). Some papules may be neoplastic (Figure 4b). Most commonly, and particularly in the groins, they precede pustules. Crusted papules may follow vesicles or pustules. In the dog crusted papules outnumber pustules in superficial pyoderma. Superficial pyoderma is uncommon in the cat and in this species the most common underlying cause of a crusted papular dermatitis is flea bite hypersensitivity (Figure 5).

Nodule A well-defined, solid elevation (Figure 6) , greater than 1 cm in diameter. Nodules are typically, although not exclusively, associated with neoplasia.

Pustule Pustules (Figure 7) are the primary lesions of superficial pyoderma, although often outnumbered by papules, crusted papules (Figure 8) and epi- dermal collarettes (Figure 9). Pustules are the primary lesions of pemphigus foliaceus but are rarely accompanied by epidermal collarettes in this disease. Pustules are also found in association with other conditions associated with secondary infection such as demodicosis.

Vol 18 No 1 / / 2008 / / Veterinary Focus / / 47

CUT-OUT AND KEEP GUIDE

Understanding

primary skin lesions

By Richard Harvey

Figure 2. More or less symmetrical crusting and linear alopecia in a Rottweiler with flea bite hypersensitivity.

Figures 1 a and 1 b. Almost total alopecia and crusting on a Cocker Spaniel with a 6 month history. Careful examination of the dog revealed a few pustules (Figure 1b).

a b

Published in IVIS with the permission of the editor Close window to return to IVIS

48 / / Veterinary Focus / / Vol 18 No 1 / / 2008

UNDERSTANDING PRIMARY SKIN LESIONS

Comedones Comedones (Figure 10) result from blockage of a follicular orifice by debris and sebaceous material. Typically black in appearance they are associated with feline acne, demodicosis and hyperadrenocorticism in particular.

Erosion and ulcer Erosions are considered to be superficial, whereas ulcers erode beneath the basement

membrane, exposing the dermis. Acral granulo- mas (Figure 11) typically present as erosions on the distal limb.

Sinus A sinus (Figure 12) is a manifestation of a deep infection that has broken through the basement membrane, or of a dermal lesion (such as panni- culitis) that has broken through the skin.

Figure 10. Comedones, in a case of hyper- adrenocorticism.

Figure 11. Erosion is a lesion in which the epithelium is taken down to the basement membrane, any deeper and it is an ulcer. Acral granulomas often present as erosions on the distal limb.

Figure 12. Sinus formation is usually a sign of deep pyoderma, panniculitis, atypical mycobacterial infection or deep fungal infection.

Figure 5. Crusted papules on the dorsum of a cat, the most common presentation of flea bite hypersensitivity.

Figure 7. Solitary, well-formed pustule. Often associated with bacterial infection, pustules may also follow inoculation by sharp vegetation or be the lesions of autoimmune disease.

Figure 6. A solitary nodule, typically, although not exclusively a tumor.

Figure 9. Epidermal collarettes, typically associated with superficial pyoderma.

Figure 8. Superficial pyoderma in a young German Shepherd is characterized by erythematous macules and papules, a few pustules and post-inflammatory crusted papules.

PRIMARY LESIONS

Figure 4b. Erythematous papules on the ventrum of a dog with allergic contact dermatitis.

Figure 4a. Erythematous papule on the pinna of a dog, in this case a mast cell tumor.

Figure 3. Erythematous macules on the dorsal neck of a dog with hyperadrenocorticism.