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UNE medical biochemistry Unit 1 Test questions and answers correctly explained., Exams of Medical Biochemistry

Rasmussen College - IllinoisMedical Biochemistry

UNE medical biochemistry Unit 1 Test questions and answers correctly explained.

Typology: Exams

2024/2025

Available from 07/03/2025

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annie-wanjiru 🇺🇸

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UNE medical biochemistry Unit 1 Test
questions and answers correctly explained.
Changes in the physiological variables listed below can alter the affinity of hemoglobin
for oxygen. Which of the following will lower the affinity of hemoglobin for oxygen?
a) decrease in protons
b) increase in 2,3 bisphosphoglycerate (BPG)
c) increase in pH
d) decrease in CO2 - correct answers.Increase in 2,3 bisphosphoglycerate (BPG)
Domains are common structural elements that retain a particular function within the
protein. Which of the following is an example of a protein domain?
a) a prosthetic group such as heme
b) irregular coils and loops
c) an arrangement of β-strands connected by α- helixes
d) a single α- helix - correct answers.An arrangement of β-strands connected by α-
helixes
A 22-year-old female is diagnosed with acute pancreatitis. Elevation of which of the
following serum enzymes would be consistent with this diagnosis?
a) lactate dehydrogenase
b) amylase
c) troponin
d) creatine kinase - correct answers.amylase
Movement of ammonia from an amino acid to an alpha-keto acid involves a family of
enzymes best categorized as:
a) transferases
pf3
pf4
pf5

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UNE medical biochemistry Unit 1 Test

questions and answers correctly explained.

Changes in the physiological variables listed below can alter the affinity of hemoglobin for oxygen. Which of the following will lower the affinity of hemoglobin for oxygen? a) decrease in protons b) increase in 2,3 bisphosphoglycerate (BPG) c) increase in pH d) decrease in CO2 - correct answers.Increase in 2,3 bisphosphoglycerate (BPG) Domains are common structural elements that retain a particular function within the protein. Which of the following is an example of a protein domain? a) a prosthetic group such as heme b) irregular coils and loops c) an arrangement of β-strands connected by α- helixes d) a single α- helix - correct answers.An arrangement of β-strands connected by α- helixes A 22-year-old female is diagnosed with acute pancreatitis. Elevation of which of the following serum enzymes would be consistent with this diagnosis? a) lactate dehydrogenase b) amylase c) troponin d) creatine kinase - correct answers.amylase Movement of ammonia from an amino acid to an alpha-keto acid involves a family of enzymes best categorized as: a) transferases

b) ligases c) lyases d) isomerases - correct answers.transferases Which of the following proteins is likely to have quaternary structure? a) a protein that contains both α-helix and β-sheet secondary structures b) a multimeric protein that contains multiple peptide chains c) a small protein consisting of a single amino acid chain d) a large transmemberane protein with seven alpha helical domains - correct answers.a multimeric protein that contains multiple peptide chains Cleavage of fructose 1, 6 bisphosphate to dihydroxyacetone and glyceraldehyde 3- phosphate is achieved by what class of enzymes? a) ligase b) lyase c) transferase d) hydrolase - correct answers.Lyase Which of the following best describes the structure of heme? a) a planar porphyrin ring that binds iron b) a nicotinamide structure that is readily oxidized c) an n-linked glycosylation d) a negatively charged phosphate group - correct answers.a planar porphyrin ring that binds iron Prosthetic groups are complex nonprotein molecules that participate in catalysis by providing functional groups that form a covalent intermediate between the enzyme and the substrate. Which of the following is an example of a coenzyme or cofactor that participates in a covalent catalysis reaction? a) ATP b) OH- c) NADH d) pyridoxal phosphate - correct answers.pyridoxal phsophate Which of the following best describes tertiary structure? a) interactions between differing subunits of a protein b) interactions between α-helixes and β-pleated sheets to form a domain c) interactions between amino acids 4 residues away from each other d) interactions between single amino acids adjacent to one another - correct answers.interactions between α-helixes and β-pleated sheets to form a domain

The following represents a series of reactions. As levels of B increase, this will decrease the conversion of S3 to B. Which of the following best describes this type of regulation in a biosynthetic pathway? a) feedback inhibition b) feedforward activation c) covalent regulation d) inducible regulation - correct answers.feedback inhibition The association of DNA and histones can be modified by histone acetylation. A decrease in histone acetylation will have which of the following impacts on the assocation of DNA and histones? a) increase DNA:histone association b) decrease DNA:histone association c) have no effect - correct answers.Increase DNA:histone association If a mutation is made within the active site of an enzyme resulting in a decrease of it's Km value, which of the following will be true with respect to enzyme kinetics? a) the Vmax of the reaction will increase b) the enzyme will require a higher substrate concentration to achieve 1/2 Vmax c) the concentration of substrate needed to reach 1/2 Vmax will not change d) the enzyme will require a lower substrate concentration to reach 1/2 Vmax - correct answers.The enzyme will require a lower substrate concentration to reach 1/2 Vmax An example of enzyme activation by cleavage is best illustrated by which of the following? a) activation of chymotrypsinogen to chymotrypsin b) phosphorylation of muscle glycogen phosphorylase c) cortisol binding an intracellular receptor d) activation of adenylyl cyclase to generate cAMP - correct answers.activation of chymotrypsinogen to chymotrypsin As electrons flow through complexes in the inner mitochondrial membrane, protons are pumped from the matrix to the intermembrane space. Which of the following statements is most reflective of the pH in the intermembrane space? a) the pH in the matrix and the intermembrane space are the same b) the pH is higher in the matrix c) the pH is lower in the matrix - correct answers.the pH is higher in the matrix In the malate/aspartate shuttle, glutamate is converted to _________ in the mitochondria while aspartate is converted to ___________ in the cytosol. - correct answers.a-ketoglutarate; oxaloacetate

Which of the following components of the electron transport chain is not bound to the mitochondrial membrane? - correct answers.Co Q A 19-year-old male is being evaluated for muscle weakness. A muscle biopsy revealed normal states of succinate oxidation but very low rates of pyruvate oxidation. Further testing determined normal levels of enzymatic activity in both malate dehydrogenase and pyruvate dehydrogenase. Based on this data, the patient may have a mutation in a gene encoding for which mitochondrial protein? a) complex I b) complex II c) complex III d) complex IV e) complex V - correct answers.Complex I (NADH Q-oxidoreductase) Succinate is a substrate for which complex in the electron transport chain? a) complex I b) complex II c) complex IV d) complex V - correct answers.Complex II (succinate-Q reductase) The malate-aspartate shuttle is used to move reducing equivalents of cytosolic NADH into the mitochondria where it can be oxidized. Which of the following compounds is used to move the reducing equivalents from cytosolic NADH into the mitochondria? a) aspartate b) malate c) glutamate d) oxaloacetate - correct answers.Malate Which of the following would be consistent with an exergonic reaction? a) ΔG would be negative b) ΔS would be negative c) ΔS would be positive d) ΔG would be positive - correct answers.ΔG would be negative Dinitrophenol is an uncoupler of the electron transport chain. The addition of dinitrophenol will have which of the following impacts? a) decrease the pH of the intermembrane space b) increase oxygen consumption c) increase ATP production d) decrease oxidation of NADH - correct answers.increase oxygen consumption