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Understanding Viruses: Structure, Replication, and Impact, Study Guides, Projects, Research of Virology

An introduction to viruses, their estimated numbers, and their relationship with bacteria. It explains what viruses are, their features, and how they differ from bacteria. The document also covers the structure of viruses, including their capsids, envelopes, and genomes.

Typology: Study Guides, Projects, Research

2021/2022

Uploaded on 09/12/2022

laksh
laksh 🇺🇸

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Name: _____________________________________ Virus Active
Read
Introduction
Scientists estimate that there are roughly 1031 viruses at any given moment^11start
superscript, 1, end superscript. That’s a one with 31 zeroes after it! If you were somehow
able to wrangle up all 1031 of these viruses and line them end-to-end, your virus column
would extend nearly 200 light years into space. To put it another way, there are over ten
million times more viruses on Earth than there are stars in the entire universe
Does that mean there are 1031 viruses just waiting to infect us? Actually, most of these
viruses are found in oceans, where they attack bacteria and other microbes. It may seem
odd that bacteria can get a virus, but scientists think that every kind of living organism is
probably host to at least one virus!
What is a Virus?
A virus is a tiny, infectious particle that can reproduce only by infecting a host cell. Viruses
"commandeer" the host cell and use its resources to make more viruses, basically
reprogramming it to become a virus factory. Because they can't reproduce by themselves
(without a host), viruses are not considered living. Nor do viruses have cells: they're very
small, much smaller than the cells of living things, and are basically just packages of nucleic
acid and protein.
Still, viruses have some important features in common with cell-based life. For instance,
they have nucleic acid genomes based on the same genetic code that's used in your cells
(and the cells of all living creatures). Also, like cell-based life, viruses have genetic variation
and can evolve. So, even though they don't meet the definition of life, viruses seem to be in
a "questionable" zone. (Maybe viruses are actually undead, like zombies or vampires!)
1. A virus can only reproduce by ________________________ a cell.
2. Are viruses living or nonliving?
3. Are viruses larger or smaller then cells?
4. All viruses have nucleic acid __________________ based on the same genetic code used
in your cells.
How are viruses different from bacteria?
Even though they can both make us sick, bacteria and viruses are very different at the
biological level. Bacteria are small and single-celled, but they are living organisms that do
not depend on a host cell to reproduce. Because of these differences, bacterial and viral
infections are treated very differently. For instance, antibiotics are only helpful against
bacteria, not viruses.
Bacteria are also much bigger than viruses. The diameter of a typical virus is
about 20 - 30 nanometers. This is considerably smaller than a typical E. coli bacterium,
which has a diameter of roughly 1000 nanometers! Tens of millions of viruses could fit on
the head of a pin.
5. Are viruses and bacteria the same or different?
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Name: _____________________________________ Virus Active Read Introduction Scientists estimate that there are roughly 1031 viruses at any given moment^11start superscript, 1, end superscript. That’s a one with 31 zeroes after it! If you were somehow able to wrangle up all 1031 of these viruses and line them end-to-end, your virus column would extend nearly 200 light years into space. To put it another way, there are over ten million times more viruses on Earth than there are stars in the entire universe Does that mean there are 1031 viruses just waiting to infect us? Actually, most of these viruses are found in oceans, where they attack bacteria and other microbes. It may seem odd that bacteria can get a virus, but scientists think that every kind of living organism is probably host to at least one virus! What is a Virus? A virus is a tiny, infectious particle that can reproduce only by infecting a host cell. Viruses "commandeer" the host cell and use its resources to make more viruses, basically reprogramming it to become a virus factory. Because they can't reproduce by themselves (without a host), viruses are not considered living. Nor do viruses have cells: they're very small, much smaller than the cells of living things, and are basically just packages of nucleic acid and protein. Still, viruses have some important features in common with cell-based life. For instance, they have nucleic acid genomes based on the same genetic code that's used in your cells (and the cells of all living creatures). Also, like cell-based life, viruses have genetic variation and can evolve. So, even though they don't meet the definition of life, viruses seem to be in a "questionable" zone. (Maybe viruses are actually undead, like zombies or vampires!)

  1. A virus can only reproduce by ________________________ a cell.
  2. Are viruses living or nonliving?
  3. Are viruses larger or smaller then cells?
  4. All viruses have nucleic acid __________________ based on the same genetic code used in your cells. How are viruses different from bacteria? Even though they can both make us sick, bacteria and viruses are very different at the biological level. Bacteria are small and single-celled, but they are living organisms that do not depend on a host cell to reproduce. Because of these differences, bacterial and viral infections are treated very differently. For instance, antibiotics are only helpful against bacteria, not viruses. Bacteria are also much bigger than viruses. The diameter of a typical virus is about 20 - 30 nanometers. This is considerably smaller than a typical E. coli bacterium, which has a diameter of roughly 1000 nanometers! Tens of millions of viruses could fit on the head of a pin.
  5. Are viruses and bacteria the same or different?
  1. What is larger a virus or a bacteria cell? The structure of a virus There are a lot of different viruses in the world. So, viruses vary a ton in their sizes, shapes, and life cycles. Viruses do, however, have a few key features in common. These include:
  • A protective protein shell, or capsid
  • A nucleic acid genome made of DNA or RNA, tucked inside of the capsid
  • A layer of membrane called the envelope (some but not all viruses) Let's take a closer look at these features.
  1. What are the 3 things all viruses have? a. b. c. Virus Capsids The capsid, or protein shell, of a virus is made up of many protein molecules (not just one big, hollow one). The proteins join to make units called capsomers, which together make up the capsid. Capsid proteins are always encoded by the virus genome, meaning that it’s the virus (not the host cell) that provides instructions for making them.
  2. The capsid is made of ____________________
  3. Who has the instructions for making the capsid? Virus Envelopes In addition to the capsid, some viruses also have an external lipid membrane known as an envelope, which surrounds the entire capsid. Viruses with envelopes do not provide instructions for the envelope lipids. Instead, they "borrow" a patch from the host membranes on their way out of the cell. Envelopes do, however, contain proteins that are specified by the virus, which often help viral particles bind to host cells.
  4. The envelope is made up of what type of molecules?
  5. Do they make their own envelop or steal it?