

Study with the several resources on Docsity
Earn points by helping other students or get them with a premium plan
Prepare for your exams
Study with the several resources on Docsity
Earn points to download
Earn points by helping other students or get them with a premium plan
Community
Ask the community for help and clear up your study doubts
Discover the best universities in your country according to Docsity users
Free resources
Download our free guides on studying techniques, anxiety management strategies, and thesis advice from Docsity tutors
Definitions and explanations of key terms related to signal transduction, specifically focusing on g protein-coupled receptors (gpcrs) and phosphoinositides. Gpcrs are a group of receptors that span the plasma membrane seven times, and their binding to ligands causes a conformational change that increases their affinity for a heterotrimeric g protein, initiating a response within the cell. Phosphoinositides, a negatively charged phospholipid, play a role in the cytosolic side of eukaryotic cell membranes. Irss (insulin receptor substrates) are protein substrates that get phosphorylated in response to insulin, binding and activating various 'downstream' effectors.
Typology: Quizzes
1 / 2
This page cannot be seen from the preview
Don't miss anything!
TERM 1
DEFINITION 1 the overall process in which information carried by extracellular messenger molecule is translated into changes that occur inside the cell TERM 2
DEFINITION 2 G protein couled receptor TERM 3
DEFINITION 3 a group of related receptors that span the plasma membrane seven times. the binding of this ligand to its specific receptor causes a chang in the conformation of the receptor tha increases it afinity for a heterotrimic G protein initiating a response within the cell. TERM 4
DEFINITION 4 Phosphatidylinositol (abbreviated PtdIns, or PI) is a negatively charged phospholipid and a minor component in the cytosolic side of eukaryotic cell membranes. TERM 5
DEFINITION 5 can be present in at least two alternate conformations, as acitive GDP molecules
TERM 6
DEFINITION 6 Insulin receptor substrate TERM 7
DEFINITION 7 protein substrate that when phosphorylated in response to insulin, bind and activates a variety of 'downstream' effectors